Development of Innovative Proton and Neutron Therapies With High Cancer Specificity by ‘Hijacking’ the Intracellular Chemistry of Haem Biosynthesis
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CENTRUM VYZKUMU REZ s.r.o.

After its establishment in 2002, the main objective of the new research company, and subsequently its mission, became research, development and innovation in the energy sector, with a relatively broad scope, especially in the nuclear field. In order to be able to carry out research activities and to achieve excellent results also on an international scale, it was necessary to build a modern research base and to create adequate working teams with the necessary know-how. Today, we have not only a number of renowned experts, but also a unique experimental infrastructure including the LVR-15 and LR-0 research reactors, process loops, hot cells and a full range of state-of-the-art laboratories.

Role within NuCapCure

The involvement of the CVR within the NuCapCure project is to adapt the neutron beams of the LVR-15 research reactor for the needs of in-vitro (WP3) and in-vivo (WP4) studies focusing on exposure by thermal neutrons and perform the irradiations afterwards. Further the research infrastructure comprising the gamma spectrometry laboratory and the biological laboratory of CVR will house the research activities with the irradiated samples or laboratory animals. CVR can built on its experience with the utilization of neutron beams and their modifications as well as practical experience in in boron neutron capture therapy in its earlier stages leading even to pilot patient studies at the turn of the millennium.

Main contact(s)

Photo of Jaroslav Šoltés

Jaroslav Šoltés

Project Leader

Photo of Daniela Veselá

Daniela Veselá

Project Manager

Our perspective on NuCapCure

This project is an opportunity for the CVŘ to resume its activity in the Boron Neutron Capture Therapy from the late 1990s and to participate in the state-of-the-art cancer treatment research.

Jaroslav Šoltés, Project Leader

CENTRUM VYZKUMU REZ s.r.o.